Brian R. Dorn, Attorney

Dr. Dorn practices intellectual property law with an emphasis on patent prosecution and opinion work. He advises clients regarding patent filing strategy, clearance searching, patentability searching, validity analysis, and infringement analysis. Dr. Dorn's practice is concentrated in biotechnology and pharmaceuticals. His experience includes prosecuting patents and providing regarding stem cells, therapeutic peptides, humanized antibodies, small molecule pharmaceuticals and therapeutic uses, pharmaceutical delivery systems, antimicrobials, diagnostic and immuno-assays, phage display systems, microarrays, transgenic animals, and medical device coatings.

Dr. Dorn's practice also includes international work. He works with patent attorneys in other countries to obtain patents in those specific countries and in the U.S. for non-U.S. applicants.

Dr. Dorn also serves on the Advisory Board for the University of Minnesota's Joint Degree Program in Law, Health & the Life Sciences. As a member of the Advisory Board, Dr. Dorn is among a group of attorneys, physicians, researchers and policy makers who counsel the program and mentor joint degree students.

Scientific Peer-Reviewed Publications

Dorn, B.R., Leung, K.-P., and Progulske-Fox, A. Invasion of human oral epithelial cells by Prevotella intermedia. Infection and Immunity. 66: 6054-6057 (1998). View

Dorn, B.R., Dunn, William A., Jr., and Progulske-Fox, A. Invasion of human coronary artery cells by periodontal pathogens. Infection and Immunity. 67: 5792-5798 (1999). View

Progulske-Fox, A., Kozarov, E., Dorn, B., Dunn, W., Burks, J., and Wu, Y. Virulence factors of Porphyromonas gingivalis and invasion of cells of the cardiovascular system. Journal of Periodontal Research. 34: 393-399 (1999). View

Dorn, B.R., Burks, J.N., Seifert, K.N., and Progulske-Fox, A. Invasion of endothelial and epithelial cells by strains of Porphyromonas gingivalis. FEMS Microbiology Letters. 187: 139-144 (2000). View

Dorn, B.R., Dunn, William A., Jr., and Progulske-Fox, A. Porphyromonas gingivalis traffics to autophagosomes in human coronary artery endothelial cells. Infection and Immunity. 69: 5698-5708 (2001). View

Dorn, B.R., Dunn, William A., Jr., and Progulske-Fox, A. Bacterial interactions with the autophagic pathway. Cellular Microbiology. 4: 1-10 (2002). (Cover Article). View

Dorn, B.R., Harris, L.J., Wujick, C.T., Vertucci, F.J, and Progulske-Fox, A. Porphyromonas endodontalis in vitro invasion of vascular cells. International Journal of Endodontics. 35: 366-371 (2002). View

Kozarov, E.V., Dorn, B.R., Raynald, M., Shelburne, C.E., Dunn, Jr., W.A., and Progulske-Fox, A. Human Atherosclerotic Plaque Contains Viable Invasive Actinobacillus actinomycetemcomitans and Porphyromonas gingivalis. Arteriosclerosis, Thrombosis, and Vascular Biology. 25: e17-e18 (2005). View

Jandik, K.A., Bélanger, M., Low, S.L., Dorn B.R., Yang, M.C.K., and Progulske-Fox, A. Invasive differences among Porphyromonas gingivalis strains from healthy and disease periodontal sites. Journal of Periodontal Research. 43: 524-530 (2008). View

Book Chapters

Dunn, W.A., Jr., B.R. Dorn, and A. Progulske-Fox. Trafficking of bacterial pathogens to autophagosomes, p. 233-240. D.J. Klionsky (ed.), Autophagy. Landes Bioscience. Georgetown, Texas (2003). View

Brian R. Dorn. Providing Real Value to Clients, M. Kraham (ed.), Inside the Minds: Life Sciences Law Client Strategies . Aspatore Books. Boston, Massachusetts (2007).

Legal Publications

Brian R. Dorn, Chakrabarty in the Era of Genomics , 6 Journal of Technology Law & Policy 101 (2001) (selected as Best Case Comment of the Spring 2001 write-on competition).

Anthony R. Zeuli and Brian R. Dorn, Perspectives on the Law: Intellectual Property , Bench & Bar, July 2002, at 33.

Anthony R. Zeuli and Brian R. Dorn, Perspectives on the Law: Intellectual Property , Bench & Bar, April 2004, at 11.

Presentations

Dorn, B.R. and Progulske-Fox, A. (1998). Invasion of human coronary artery endothelial cells and coronary smooth muscle cells by periodontal pathogens. Abstract presented at the Conference on Microbes, Haemostasis and Vascular Biology co-sponsored by the American Society for Microbiology, Texas A&M University, and the World Health Organization. Galveston, Texas.

Dorn, B.R. and Progulske-Fox, A. (1998) Invasion of human coronary artery cells by Porphyromonas gingivalis . Oral session presented at the General Session and Exhibition of the International Association for Dental Research. Nice, France.

Whitlock, J.A., Dorn, B.R., Burks, J.N., Kozarov, E.V., and Progulske-Fox, A. (1998). Porphyromonas gingivalis hag B/C hemagglutinin mutant exhibits reduced invasion of human oral epithelial cells. Abstract presented at the General Session and Exhibition of the International Association for Dental Research. Nice, France.

Dorn, B.R., Kozarov, E.V., and Progulske-Fox, A. (1999) Invasion of HUVEC and KB cells by Porphyromonas gingivalis . Abstract presented at the General Session and Exhibition of the International Association for Dental Research. Vancouver, Canada.

Dorn, B.R., Dunn, Jr., W.A., and Progulske-Fox, A. (1999) Porphyromonas gingivalis traffics to the autophagic pathway after invasion of HCAEC. Abstract presented at the American Society for Microbiology's Conference on A Cell Biology Approach to Microbial Pathogenesis. Portland, Oregon.

Progulske-Fox, A., Kozarov, E., Dorn, B., Dunn, W., Burks, J., and Wu, Y. (1999). Virulence factors of Porphyromonas gingivalis and invasion of cells of the cardiovascular system. Symposium presented at the International Conference on Periodontal Research. Göteborg, Sweden.

Dorn, B. R., Dunn, Jr., W. A., and Progulske-Fox, A. (2000) Intracellular trafficking of Porphyromonas gingivalis in endothelial cells. Abstract presented at the General Session and Exhibition of the International Association for Dental Research. Washington, D.C. (Finalist in both the International and the American Associations for Dental Research's Warner-Lambert Hatton graduate student competitions).

Dorn, B.R., Burks, J.N., and Progulske-Fox, A. (2000). Porphyromonas gingivalis FimA expression is not sufficient for invasion. Abstract presented at the General Session and Exhibition of the International Association for Dental Research. Washington, D.C.

Dorn, B.R., Kozarov, E.V., Harris, L., Whitlock, J.A., and Progulske-Fox, A. (2000). Both hagA and hagB Hemagglutinins of Porphyromonas gingivalis Act as Adhesins for Invasion of HCAEC. Abstract presented at the General Meeting of the American Society for Microbiology. Los Angeles, California.

Dorn, B. R., Dunn, Jr., W. A., and Progulske-Fox, A. (2000) Intracellular trafficking of Porphyromonas gingivalis in endothelial cells. Oral session presented at the University of Florida Medical Guild Graduate Student Research Competition. Gainesville, FL.

Dorn, B.R., Dunn, Jr., W.A., and Progulske-Fox, A. (2001). Porphyromonas gingivalis does not Induce Cell Death in Endothelial cells. Abstract presented at the General Session and Exhibition of the American Association for Dental Research. Chicago, Illinois.

Dorn, B.R., Dunn, Jr., W.A., and Progulske-Fox, A. (2001). Porphyromonas gingivalis persistence and exiting in endothelial cells. Abstract presented at the General Meeting of the American Society for Microbiology. Orlando, Florida.

Grants

American Association of Endodontists Foundation, Invasion of Coronary Artery Cells by Microorganisms Associated with Endodontic Infections, Co-investigator (Frank Vertucci, P.I.) 7/1/99 - 6/30/01.